abstract：:We performed a retrospective pooled analysis of 28 patients who had been diagnosed with insulin autoimmune syndrome and evaluated the prevalence of anti-insulin receptor antibodies. Dual positivity for anti-insulin and anti-insulin receptor antibodies was common (53.8%). However, these patients had a similar phenotype...

journal_title：Diabetes research and clinical practice

authors： Kim SW,Won HK,Seok H,Lee BW,Jung CH,Lee WJ,Kim JH

更新日期：2012-11-01 00:00:00

abstract：AIMS:The aim of this study was to investigate whether the polymorphism of DDAH2 is associated with type 2 diabetes and hypertension in Korean population. METHODS:Total 605 subjects were included in this study: 403 patients with type 2 diabetes and 202 non-diabetic control subjects. The SNP rs805304 and rs2272592 in DD...

journal_title：Diabetes research and clinical practice

authors： Seo HA,Kim SW,Jeon EJ,Jeong JY,Moon SS,Lee WK,Kim JG,Lee IK,Park KG

更新日期：2012-10-01 00:00:00

abstract：AIMS:To investigate the relationship of coronary artery calcium (CAC) scores with common carotid artery intima media thickness (CCA-IMT), albuminuria and inflammatory factors in type 2 diabetes. METHODS AND RESULTS:128 asymptomatic type 2 diabetic patients, with at least one cardiovascular risk factor in addition to d...

journal_title：Diabetes research and clinical practice

authors： Dayan A,Narin B,Biteker M,Aksoy S,Fotbolcu H,Duman D

更新日期：2012-10-01 00:00:00

abstract：AIMS:The aim of the study was to develop and test the feasibility of a three months web-based intervention, delivered by a smartphone to support self-management in patients with type 2 diabetes. METHODS:The intervention included use of a smartphone enabling access to daily web-based diaries and individualized written ...

journal_title：Diabetes research and clinical practice

authors： Nes AA,van Dulmen S,Eide E,Finset A,Kristjánsdóttir OB,Steen IS,Eide H

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The present study aimed to investigate whether the single nucleotide polymorphism (SNP) 276G>T (rs1501299) of the adiponectin (ADIPOQ) gene was associated with the risk of coronary artery disease (CAD) and serum adiponectin levels in a Chinese population. METHODS:The rs1501299 polymorphism of the ADIPOQ gen...

journal_title：Diabetes research and clinical practice

authors： Gui MH,Li X,Jiang SF,Gao J,Lu DR,Gao X

更新日期：2012-09-01 00:00:00

abstract：AIMS:To determine whether exendin-4 might directly improve endothelial dysfunction in aorta isolated from high-fat diet-induced obese rats. METHODS:Wistar rats were randomly divided into control and obesity (OB) groups and fed. Vascular segments of obese rats were incubated in organ bath in the presence or absence of ...

journal_title：Diabetes research and clinical practice

authors： Han L,Yu Y,Sun X,Wang B

更新日期：2012-09-01 00:00:00

abstract：:The aim of this study was to investigate the effect of resveratrol on beta cells in male C57BL/6J mice fed a high-fat diet and the possible mechanisms. Male C57BL/6J mice were randomly divided into three groups: normal control (NC) group, high-fat diet (HF) group and high-fat diet and resveratrol treatment (HFR) group...

journal_title：Diabetes research and clinical practice

authors： Zhang J,Chen L,Zheng J,Zeng T,Li H,Xiao H,Deng X,Hu X

更新日期：2012-09-01 00:00:00

abstract：:Moderate-to-vigorous physical activity (MVPA) has been shown to be inversely associated with C-reactive protein (CRP); however, the association between light intensity physical activity (LPA), and CRP is unknown. Our findings suggest that focusing on increasing MVPA, relative to LPA, may have a greater impact on infla...

journal_title：Diabetes research and clinical practice

authors： Hawkins M,Belalcazar LM,Schelbert KB,Richardson C,Ballantyne CM,Kriska A

更新日期：2012-07-01 00:00:00

abstract：:Numerous studies with compelling evidence had shown a clear relationship between dyslipidaemia and cardiovascular (CV) events in patients with diabetes mellitus. This was an observational study based on secondary data from the online registry database Adult Diabetes Control and Management (ADCM) looking into the deter...

journal_title：Diabetes research and clinical practice

authors： Chew BH,Ismail M,Lee PY,Taher SW,Haniff J,Mustapha FI,Bujang MA

更新日期：2012-06-01 00:00:00

abstract：:In a case-control analysis comparing 303 patients with diabetes and 303 without (matched on age, race, sex and height), diabetics had reduced lung diffusion (DLCO) independent of smoking, obesity, clinical heart failure, asymptomatic left ventricular systolic and diastolic dysfunction: DLCO (mean±SE: 15.5±0.9 vs. 16.4...

journal_title：Diabetes research and clinical practice

authors： Klein OL,Jones M,Lee J,Collard HR,Smith LJ

更新日期：2012-06-01 00:00:00

abstract：:The impact of hypertension, overall obesity and abdominal obesity, individually or collectively, on diabetes incidence over a period of 5 years in residents with different glucose levels is diverse, with abdominal obesity having an impact in both non-diabetic hyperglycaemia and normal groups. ...

journal_title：Diabetes research and clinical practice

authors： Qian Q,Li X,Feng B

更新日期：2012-06-01 00:00:00

abstract：:In 61 young adults with type 1 diabetes mellitus, the estimated glucose disposal rate (eGDR), a validated marker for insulin resistance, correlated positively with the prevalence of microvascular complications. In the absence of an established vascular risk calculator specific to diabetes, the eGDR may present a usefu...

journal_title：Diabetes research and clinical practice

authors： Girgis CM,Scalley BD,Park KE

更新日期：2012-06-01 00:00:00

abstract：AIMS:To validate and culturally adapt the Diabetes-specific Quality of Life Brief Clinical Inventory (DQOL-BCI) for the Iranian population. METHODS:After translation - back translation, content validity was assessed utilizing a panel of six experts. Based on a sample of 180 diabetic patients referred to two Diabetics ...

journal_title：Diabetes research and clinical practice

authors： Mirfeizi M,Jafarabadi MA,Toorzani ZM,Mohammadi SM,Azad MD,Mohammadi AV,Teimori Z

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:Several genome-wide association studies and replication analyses have identified common variation at the insulin-like binding protein 2 (IGF2BP2) gene to be associated with type 2 diabetes (T2DM). The aim of this study was to replicate in a Lebanese Arab population identified associations of IGF2BP2 variants ...

journal_title：Diabetes research and clinical practice

authors： Nemr R,Echtay A,Dashti EA,Almawi AW,Al-Busaidi AS,Keleshian SH,Irani-Hakime N,Almawi WY

更新日期：2012-05-01 00:00:00

abstract：AIM:To evaluate perceived risk, control, worry, and severity about diabetes, coronary heart disease (CHD) and stroke among individuals at increased familial risk of diabetes. METHODS:Data analyses were based on the Family Healthware™ Impact Trial. Baseline health beliefs were compared across three groups: (1) no famil...

journal_title：Diabetes research and clinical practice

authors： Dorman JS,Valdez R,Liu T,Wang C,Rubinstein WS,O'Neill SM,Acheson LS,Ruffin MT 4th,Khoury MJ

更新日期：2012-05-01 00:00:00

abstract：AIMS:We determined levels of the inflammatory marker YKL-40 in a population of patients with type 2 diabetes (T2D) and investigated the association with mortality. METHODS:In a prospective observational follow-up study, 290 patients with T2D, normoalbuminuria (n=177), microalbuminuria (n=71) and macroalbuminuria (n=42...

journal_title：Diabetes research and clinical practice

authors： Persson F,Rathcke CN,Gall MA,Parving HH,Vestergaard H,Rossing P

更新日期：2012-04-01 00:00:00

abstract：AIMS:To investigate the prevalence of undiagnosed diabetes mellitus (DM) and cardiovascular risk factors among professional drivers in Hong Kong. METHODS:Chinese professional drivers with no history of DM were invited to complete a questionnaire on their health status, followed by taking their body measurements, fasti...

journal_title：Diabetes research and clinical practice

authors： Siu SC,Wong KW,Lee KF,Lo YY,Wong CK,Chan AK,Fong DY,Lam CL

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:The serum N-terminal fragment of pro brain natriuretic peptide (NT-proBNP) level in type 2 diabetic subjects with or without diabetic nephropathy (DN) is still unclear. We aimed to evaluate the relationship between serum NT-proBNP levels and different stages of diabetic nephropathy, and identify probable fact...

journal_title：Diabetes research and clinical practice

authors： Danis R,Ozmen S,Arikan S,Gokalp D,Alyan O

更新日期：2012-03-01 00:00:00

abstract：AIMS:To determine whether intensive risk factor management reduced markers of inflammation in middle-aged and older people with type 2 diabetes who either had, or were at risk for cardiovascular disease (CVD), and whether these effects were mediated by adiposity. METHODS:The Action to Control Cardiovascular Risk in Di...

journal_title：Diabetes research and clinical practice

authors： Samaropoulos XF,Light L,Ambrosius WT,Marcovina SM,Probstfield J,Goff DC Jr

更新日期：2012-03-01 00:00:00

abstract：:Cervical necrotizing fasciitis and a descending mediastinal abscess of the neck following acute epiglottitis, life-threatening complications, is reported in a 43-year-old man with DM. The bacterial culture showed Peptostreptococcus anaerobius. The patient recovered after surgical debridement and broad-spectrum antibio...

journal_title：Diabetes research and clinical practice

authors： Ge R,Mao Y,Zhang XL,Zheng SQ

更新日期：2012-02-01 00:00:00

abstract：AIMS:To study HLA-DQB1 genes and islet cell autoantibodies against glutamic acid decarboxylase 65 (GADA) and insulinoma antigen-2 (IA-2A) in relation to diabetes post partum in mothers with diagnosed gestational diabetes mellitus (GDM). METHODS:During 2003-2004, women undergoing a 75 g oral glucose tolerance test (OGT...

journal_title：Diabetes research and clinical practice

authors： Papadopoulou A,Lynch KF,Anderberg E,Landin-Olsson M,Hansson I,Agardh CD,Lernmark Å,Berntorp K

更新日期：2012-02-01 00:00:00

abstract：AIM:To perform a network meta-analysis between long-acting insulin analogues (glargine and detemir) and Neutral Protamine Hagedorn (NPH) insulin on adults with type 1 diabetes. METHODS:A systematic review of the literature was conducted according to the Cochrane Collaboration guidelines. The search for randomized cont...

journal_title：Diabetes research and clinical practice

authors： Sanches AC,Correr CJ,Venson R,Pontarolo R

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To examine change of diagnosis in patients from the German/Austrian multicenter DPV (Diabetes Patienten Verlaufsdokumentation) database initially classified as type 2 diabetes. METHODS:Patients aged ≤20 years at onset, diagnosed between 1995 and 2010 were followed for at least 6 months. Chi-square/Wilcoxon t...

journal_title：Diabetes research and clinical practice

authors： Awa WL,Schober E,Wiegand S,Herwig J,Meissner T,Schmidt F,Molz E,Holl RW

更新日期：2011-12-01 00:00:00

abstract：:The study was to examine the effects of Sanguis draconis ethanol extract (SDEE) on streptozotocin (STZ)- and cytokine-induced β-cell damage. In vitro, SDEE did not cause cytotoxicity below 200 μg/ml, and can prevent STZ (5mM)-induced cell death and apoptosis below 100 μg/ml on RIN-m5F cells. SDEE inhibits IL-1β/IFN-γ-...

journal_title：Diabetes research and clinical practice

authors： Hu CM,Li JS,Cheah KP,Lin CW,Yu WY,Chang ML,Yeh GC,Chen SH,Cheng HW,Choy CS

更新日期：2011-12-01 00:00:00

abstract：:The hyperglycemic emergencies, diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are potentially fatal complications of uncontrolled diabetes mellitus. The incidence of DKA and the economic burden of its treatment continue to rise, but its associated mortality rate which was uniformly high has dim...

journal_title：Diabetes research and clinical practice

authors： Nyenwe EA,Kitabchi AE

更新日期：2011-12-01 00:00:00

abstract：AIM:To describe coverage, cost and care of type 1 diabetes (T1D) in 2 regions of China--Beijing and Shantou--including: METHODS:This is a mixed-methods descriptive study with three arms--coverage, cost and care. It is taking place in 4 tertiary hospitals, 3 secondary hospitals and 4 primary health facilities in Beijin...

journal_title：Diabetes research and clinical practice

authors： McGuire H,Kissimova-Skarbek K,Whiting D,Ji L

更新日期：2011-11-01 00:00:00

abstract：:We examined trends and associated factors of disability among Spanish elderly with diabetes from data of three National Health Surveys (NHS) from 2000 to 2007. Prevalence of disability was higher among diabetic elderly versus non-sufferers and increased over time. Adjusted OR for activities of daily living 1.66 (1.37-...

journal_title：Diabetes research and clinical practice

authors： Martinez-Huedo MA,Lopez de Andres A,Hernandez-Barrera V,Palacios-Ceña D,Carrasco-Garrido P,Hernandez DM,Jiménez-Garcia R

更新日期：2011-11-01 00:00:00

abstract：AIM:Sitagliptin is not associated with weight gain and has neutral effects on body weight. It is unclear whether sitagliptin treatment alters serum ghrelin levels in people with type 2 diabetes. METHODS:Forty-four subjects with type 2 diabetes were randomly assigned to receive sitagliptin or medical nutrition therapy ...

journal_title：Diabetes research and clinical practice

authors： Öz Ö,Kıyıcı S,Ersoy C,Cander S,Yorulmaz H,Gül CB,Ünal OK,Sarandol E,Kırhan E,Sığırlı D,Ertürk E,Tuncel E,Imamoğlu S

更新日期：2011-11-01 00:00:00

abstract：AIMS:Media calcification is a predictor of cardiovascular mortality in type 2 diabetes mellitus (T2DM). Undercarboxylation of some vitamin K-dependent proteins, due to genetic polymorphisms of VKORC1, can lead to calcification. We examined a potential association between VKORC1 -1639 G>A polymorphism and T2DM and, also...

journal_title：Diabetes research and clinical practice

authors： Tavridou A,Petridis I,Vasileiadis M,Ragia G,Heliopoulos I,Vargemezis V,Manolopoulos VG

更新日期：2011-11-01 00:00:00

abstract：AIMS:To determine the 10-year incidence of diabetic retinopathy (DR) and macular edema (DME), and its relationship with its risk factors in a sample of type 1 diabetes mellitus. METHODS:A total of 334 patients without diabetic retinopathy at baseline underwent a 10-year prospective study, the risk factors included: ag...

journal_title：Diabetes research and clinical practice

authors： Romero-Aroca P,Baget-Bernaldiz M,Fernandez-Ballart J,Plana-Gil N,Soler-Lluis N,Mendez-Marin I,Bautista-Perez A

更新日期：2011-10-01 00:00:00

abstract：:We observed that in isolated perfused rat kidneys, sphingosine-1-phosphate produces S1P(2) receptor-mediated vasoconstriction, and this response increased in kidneys of diabetic rats. These results suggest that the antagonists of S1P(2) receptor may have potential as drugs to control diabetes-induced vascular complica...

journal_title：Diabetes research and clinical practice

authors： Bautista-Pérez R,Arellano A,Franco M,Osorio H,Coronel I

更新日期：2011-10-01 00:00:00

abstract：:Glycated albumin (GA) is a new glycemic control indicator. GA/HbA1c ratio in autoimmune acute-onset type 1 diabetes mellitus patients was significantly higher than in type 2 diabetes mellitus patients at the time of diagnosis. This difference might reflect speed of increase in plasma glucose after the onset of diabete...

journal_title：Diabetes research and clinical practice

authors： Koga M,Murai J,Saito H,Aoki K,Kanehara H,Bando Y,Morita S,Kasayma S

更新日期：2011-10-01 00:00:00

abstract：AIM:This study investigated the molecular changes of extracorporeal shockwave therapy (ESWT) and hyperbaric oxygen therapy (HBOT) in chronic diabetic foot ulcers. METHODS:A cohort study consisted of 39 patients (44 ulcers) in the ESWT group and 38 patients (40 ulcers) in the HBOT group with similar demographic charact...

journal_title：Diabetes research and clinical practice

authors： Wang CJ,Ko JY,Kuo YR,Yang YJ

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to examine the impact of insulin sensitivity and muscle fibre composition to exercise capacity in individuals with type 2 diabetes (T2D), impaired glucose tolerance (IGT) and normal glucose tolerance (NGT). METHODS:Thirty-nine male patients with T2D, 44 male subjects with IGT and 5...

journal_title：Diabetes research and clinical practice

authors： Segerström ÅB,Elgzyri T,Eriksson KF,Groop L,Thorsson O,Wollmer P

更新日期：2011-10-01 00:00:00

abstract：:We examined cross-sectional associations of sex hormone binding globulin (SHBG) with glucose among women recent GDM (n=55). SHBG was associated with fasting glucose levels before and after adjustment for covariates (p=0.015), but not with 2-h glucose. We conclude SHBG should be explored in prospective studies in GDM w...

journal_title：Diabetes research and clinical practice

authors： Kim C,Sen A,Osborne E,Lee JM,Richardson CR

更新日期：2011-09-01 00:00:00

abstract：AIMS:To determine whether lower postprandial glucose (PPG) levels after intake of a diabetes-specific formula (DSF) compared with a standard formula were maintained after 4 weeks use. METHODS:Randomized, controlled, double-blind, parallel-group study. Forty-four type 2 diabetes patients on oral anti-diabetes medicatio...

journal_title：Diabetes research and clinical practice

authors： Lansink M,van Laere KM,Vendrig L,Rutten GE

更新日期：2011-09-01 00:00:00

abstract：AIMS:To explore associations between IRS-1 rs1801278 G>A polymorphism and metabolic syndrome (MS). METHODS:rs1801278 G>A was genotyped in 610 healthy Argentinian men. RESULTS:GA carriers had lower risk of MS (OR=0.52, P=0.045), particularly among smokers (OR=0.10, P=0.006). CONCLUSIONS:rs1801278 GA carriers had lowe...

journal_title：Diabetes research and clinical practice

authors： Pérez MS,Tellechea ML,Aranguren F,Taverna MJ,Rodríguez RG,Meroño T,Brites F,Poskus E,Frechtel GD

更新日期：2011-09-01 00:00:00

abstract：AIM:A glycated hemoglobin (HbA1c) range of 5.7-6.4% has been included as a category of increased risk for diabetes. We evaluated whether or not it is reasonable to apply this HbA1c range to Koreans. METHODS:A retrospective analysis was conducted among subjects who participated in comprehensive health check-ups annuall...

journal_title：Diabetes research and clinical practice

authors： Bae JC,Rhee EJ,Lee WY,Park SE,Park CY,Oh KW,Park SW,Kim SW

更新日期：2011-08-01 00:00:00

abstract：:Despite numerous publications according to which insulin promotes atherosclerosis, there are many observations in the last fifteen years suggesting that insulin has antiatherogenic properties. Insulin has vasodilatory, antithrombotic and anti-inflammatory effects. A good glycemic control contributes to the maximum eff...

journal_title：Diabetes research and clinical practice

authors： Karamitsos DT

更新日期：2011-08-01 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) is characterised by beta-cell failure in the setting of obesity-related insulin resistance. Progressive beta-cell dysfunction determines the course of the disease, regardless of the treatment used. There is mounting evidence that chronically elevated circulating levels of glucose and fa...

journal_title：Diabetes research and clinical practice

authors： van Raalte DH,Diamant M

更新日期：2011-08-01 00:00:00